Drug Calculation Questions – Part 1


Drug Calculation Questions

Q1: A vial of amoxicillin 500mg is reconstituted with WFI to give a concentration of 200mg/ml. Calculate the volume of this solution to be drawn up for injection if the preparation is for 120mg.

  •  0.7 ml
  •  1.6 ml
  •  0.6 ml
  •  8.3 ml

Q2: Doctor’s Order: Nafcillin 500mg po pc; Available: Nafcillin 1 gm tab (scored). How many tabs will you administer per day?

  •  2.5 tabs
  •  2 tabs
  •  1.5 tabs
  •  1 tab

Q3: 450 mg of aspirin is required. Stock on hand is 300mg tablets. How many tablets should be given?

  •  2 tablets
  •  1 ¾ tablets
  •  1 ⅔ tablets
  •  1 ½ tablets

Q4: Doctor’s order: 1.5 L of NS to be infused over 7 hours; Drop factor: 15 gtt/ml. What flow rate (mL/hr) will you set on the IV infusion pump?

  •  53.6 ml/hr
  •  214.3 ml/hr
  •  35.7 ml/hr
  •  142.9 ml/hr

Q5: Your patient has had the following intake: 2 ½ cups of coffee (240 mL/cup), 11.5 oz of grape juice, ¾ qt of milk, 320 mL of diet coke, 1¼ L of D5W IV, and 2 oz of grits. What will you record as the total intake in mL for this patient?

  •  2,325 ml
  •  3,265 ml
  •  3,325 ml
  •  2,235 ml

Q6: Doctor’s Order: Demorol 50 mg IVP q 6 hr prn pain: Available: Demerol 75 mg/1.3 mL. How many mL will you administer?

  •  0.87 ml
  •  1.87ml
  •  2ml
  •  2.87ml

Q7: Doctor’s Order: Infuse 50 mg of Amphotericin b in 250 mL NS over 4 hr 15 min; Drop factor: 12 gtt/ml. What flow rate (mL /hr) will you set on the IV infusion pump?

  •  11.8 ml/hr
  •  58.8 ml/hr
  •  14.1 ml/hr
  •  60.2 ml/hr

Q8: 800ml of fluid is to be given IV. The fluid is running at 70ml/hr for the first 5 hours then the rate is reduced to 60ml/hr. Calculate the total time taken to give 800ml.

  •  11 hours 20 minutes
  •  9 hours
  •  10 hours 25 minutes
  •  12 hours 30 minutes

Q9: A patient is to be given amoxicillin 175mg. What volume of solution should be drawn up for the injection if the concentration after dilution with water for injection is 300mg/ml?

  •  0.6 ml
  •  0.7 ml
  •  1.7 ml
  •  0.9 ml

Q10: A patient has been prescribed 1L of a saline solution. The rate is set at 150 ml/hr. How long will the infusion take?

  •  5 hours and 20 minutes
  •  4 hours and 40 minutes
  •  6 hours and 10 minutes
  •  6 hours and 36 minutes

Q11: Over a period of 9 hours a patient is to receive half a liter of dextrose 4 % in 1/5 normal saline via a volumetric infusion pump. At what flow rate should the pump be set?

  •  24 ml/hr
  •  55.5 ml/hr
  •  180 ml/hr
  •  1.8 ml/hr

Q12: 700ml of saline solution is to be given over 8 hours. The IV set delivers 20 drops/ml. What is the required drip rate?

  •  18.3 drops/min
  •  49.5 drops/min
  •  29.2 drops/min
  •  32.7 drops/min

Q13: Doctor’s Order: bumex 0.8 mg IV bolus bid; Reconstitution instructions: Constitute to 1,000 micrograms/ 3.1 mL with 4.8 mL of 5% Dextrose Water for Injection. How many mL will you administer?

  •  2 ml
  •  3.5 ml
  •  3 ml
  •  2.5 ml

Q14: A patient is prescribed 120 ml of Hartmann’s solution to be given over 5 hours. The microdrip delivers 60 drops/ml. calculate the required drip rate in drops/min

  •  20 drops/min
  •  2.5 drops/min
  •  24 drops/min
  •  32 drops/min

Q15: Doctor’s order: Synthroid 75 mcg po daily; Available: Synthroid 0.15mg tab (scored). How many tab will you administer?

  •  1 tab
  •  0.5 tab
  •  2 tabs
  •  1.5 tabs

Q16: A solution contains paractamol 120mg/5ml. How many milligrams of paracetamol are in 40 ml of the solution?

  •  600 mg
  •  960 mg
  •  320 mg
  •  160 mg

Q17: One gram of dextrose provides 16kj of energy. How many kilojoules does a patient receive from an infusion of half a liter of dextrose?

  •  32kj
  •  16kj
  •  8kj
  •  4kj

Q18: A patient is prescribed phenobarbitone 140mg. stock ampoules contain 200mg/ml. what volume must be withdrawn for injection?

  •  0.7 ml
  •  1.4 ml
  •  6 ml
  •  0.6 ml

Q19: Doctor’s order: Diuril 1.8 mg/kg pot id; Available: Diuril 12.5 mg caps. How many caps will you administer for each dose to a 14 kg child?

  •  2 caps
  •  2.5 caps
  •  3 caps
  •  1.5 caps

Q20: Doctor’s order: Infuse 1200 mL of 0.45% Normal Saline at 125 mL/hr; Drop Factor: 12gtt/ml. How many gtt/min will you regulate the IV?

  •  2 gtt/min
  •  12 gtt/min
  •  25 gtt/min
  •  27 gtt/min

Q21: A post-operative patient is to receive a PCA infusion of fentanyl 350 micrograms in 35 ml of normal saline via a syringe pump. The PCA is set to give a bolus dose of 1 ml each time the button is pressed. What is the concentration of the fentanyl in the saline solution?

  •  0.01 mg/ml
  •  0.35 mg/ml
  •  1 mg/ml
  •  0.1 mg/ml

Q22: Doctor’s Order: Cleocin Oral Susp 600 mg po qid; Directions for mixing: Add 100 mL of water and shake vigorously. Each 2.5 mL will contain 100 mg of Cleocin. How many tsp of Cleocin will you administer?

  •  3 tsp
  •  5 tsp
  •  3.5 tsp
  •  1 tsp

Q23: Doctor’s Order: Heparin 7,855 units Sub Q bid; available; Heparin 10,000 units per ml. How many mL will you administer?

  •  0.79 ml
  •  1.79 ml
  •  0.17 ml
  •  1.17 ml

Q24: 400mg of penicillin is to be given IV. One hand is penicillin 600mg in 2 ml. What volumes should be drawn up?

  •  1.3 ml
  •  3 ml
  •  0.7 ml
  •  1.6 ml

Q25: Doctor order: Rocephin 0.5 grams in 250 mL of D5W to infuse IVPB 45 minutes; Drop factor: 12 gtt/ml. How many gtt/ min will you regulate the IVPB?

  •  6 gtt/min
  •  30 gtt/min
  •  67 gtt/min
  •  87 gtt/min

Q26: Doctor’s order: Tylenol supp 1 g prq q 6 hr prn temp >101; available: Tylenol supp 325 mg (scored). How many supp will you administer?

  •  2 supp
  •  1 supp
  •  3 supp
  •  5 supp

Q27: Mrs B has been ordered 100 ml to be infused over 45 minutes via a 20 drops/ml giving set. What drip rate should be set?

  •  50 drops per minute
  •  44 drops per minute
  •  41 drops per minute
  •  52 drops per minute

Q28: Doctor’s order: Streptomycin 1.75 mg /lb IM q 12 hr; Available: Streptomycin 0.35 g/ 2.3 mL. How many mL will you administer a day to a 59 kg patient?

  •  1.5 ml
  •  2ml
  •  2.5 ml
  •  3ml

Q29: Doctor order: Mandol 300 mg in 50 mL of D5W to infuse IVPB 15 minutes; drop factor: 10 gtt/mL. How many mL/hr will you set on the IV infusion pump?

  •  200 ml/hr
  •  87.5 ml/hr
  •  3.3 ml/hr
  •  50 ml/hr

Q30: Doctor’s Order: Kantamycin 7.5 mg/kg IM q 12 hr; Available: Kantamycin 0.35 gm/mL. How many mL will you administer for each dose to a 71 kg patient?

  •  2 ml
  •  1 ml
  •  2.5 ml
  •  1.5 ml

Q31: One liter of Hartmann’s solution is to be given over 12 hours. Calculate the flow rate of a volumetric infusion pump

  •  1.4 ml/hr
  •  16.6 ml/hr
  •  83.3 ml/hr
  •  72 ml/hr

Q32: A Patient is to be given co-amoxiclav. The Recommended dosage is 20mg/kg/day, 3 doses per day. Calculate the size of a single dose if the patient’s weight is 24kg

  •  160 mg
  •  60 mg
  •  120 mg
  •  180 mg

Q33: At 22H00 hours on Thursday, 1 Liter of Saline is set to run at 80ml/hr. When will the infusion be finished:

  •  08:30 AM
  •  06:00 AM
  •  12:00 PM
  •  10:30 AM

Q34: Doctor’s order: Tazidime 0.3 g Im tid; Reconstitution instructions: For IM solution add 1.5 mL of diluent. Shake to dissolve. Provides an approximate volume of 1.8 mL (280mg/mL). How many mL will you give?

  •  1.9 ml
  •  2 ml
  •  3 ml
  •  1.1 ml

Q35: Doctor’s order: Sulfasalazine Oral susp 500 mg q 6 hr; Directions for mixing: Add 125mL of water and shake well. Each tbsp, will yield 1.5 g of Sulfasalazine. How many mL will you give?

  •  5 mL
  •  15 mL
  •  100 mL
  •  2 mL

Answers

  1. 0.6 ml
  2. 1.5 tabs
  3. 1 ½ tablets
  4. 53.6 ml/hr
  5. 3,265 ml
  6. 0.87 ml
  7. 58.8 ml/hr
  8. 12 hours 30 minutes
  9. 0.6 ml 
  10. 6 hours and 36 minutes
  11. 55.5 ml/hr
  12. 29.2 drops/min
  13. 2.5 ml
  14. 24 drops/min
  15. 0.5 tab
  16. 960 mg
  17. 8kj
  18. 0.7 ml
  19. 2 caps
  20. 25 gtt/min
  21. 0.01 mg/ml
  22. 3 tsp
  23. 0.79 ml
  24. 1.3 ml
  25. 67 gtt/min
  26. 3 supp
  27. 44 drops per minute
  28. 3ml
  29. 200 ml/hr
  30. 1.5 ml
  31. 83.3 ml/hr
  32. 160 mg
  33. 10:30 AM
  34. 1.1 ml
  35. 5 mL
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